ALLEGRA - Model THV -Transcatheter Heart Valve for Aortic Stenosis

The ALLEGRA Transcatheter Heart Valve (THV) is engineered for treating severe calcified aortic valve stenosis, focusing on maintaining optimal hemodynamic performance with single-digit mean pressure gradients and expansive effective orifice areas. Designed for high-risk patients, the ALLEGRA leverages a unique self-expanding stent frame that promotes effective anchoring and sealing while allowing a flexible outflow for a wider valve opening. This design addresses the demands of both small annuli and valve-in-valve procedures ensuring minimal stress on leaflets, which translates to enhanced durability. Furthermore, TissGUARD technology aids in tissue protection by combining anti-calcification treatment with stress-reducing features. With a supra-annular valve position, it achieves physiological flow patterns that reduce gradients, platelet activation, and paravalvular leak, extending the valve's functionality. Additionally, its design maintains access to coronary ostia, preparing for potential future interventions.