Model TCB004 -Undisclosed CAR-T

TCB004 is a gamma delta CAR-T product for the treatment of AML redirected against an undisclosed target antigen. The co-stim CAR structure on TCB004 prevents toxicity against healthy cells and is ideally suited for targeting AML where finding a target ubiquitously and exclusively presented on diseased cells has so far proved impossible. AML is a cancer characterized by infiltration of the bone marrow, blood, and other tissues by proliferative, clonal, poorly differentiated cells of the hematopoietic system and is predicted to affect 22,000 people per year in the US.