VeraPrep ABAS - Heterophilic Antibodies

Although the cause of anti-streptavidin antibodies is not fully known and under debate, one possible cause could be from the bacterium S. avidinii. It is thought that many people are exposed to these bacteria in daily life and could develop an immunological reaction to it. The body can create anti-biotin antibodies as a result of high circulating biotin levels often found in patients taking over the counter biotin supplements or high-dose biotin therapy. Unfortunately, ABAS antibodies can interfere with certain lab tests and cause incorrect results. Similar to biotin interference, ABAS interference falsely decreases test signal which can result in a false high or low test result depending on the assay format.

To mitigate this growing problem, Veravas has created a novel product that does not bind free biotin but can specifically detect and remove both anti-streptavidin and anti-biotin interference from the same sample and improve confidence in test results.