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Mtoz Biolabs Lung Cancer Services

4 services found

MtoZ Biolabs - mAb Antibody Sequencing and Recombinant Expression Services

MtoZ Biolabs - mAb Antibody Sequencing and Recombinant Expression Services

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
The inauguration of monoclonal antibodies (mAbs), derived from mice, were immunogenic in humans. These molecules were first synthesized in 1975 by Georges Köhler and César Milstein through the use of hybridoma technology. Later, in 1984, another milestone was achieved with the production of chimeric human antibodies via recombinant DNA technology. Hybridoma technology facilitates the creation of ...
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MtoZ Biolabs - Biosimilar Assessment Service

MtoZ Biolabs - Biosimilar Assessment Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Biosimilars are biological products that are highly similar to an approved original biological drug (reference or brand drug) without any clinically meaningful differences in quality, safety, or efficacy compared to those approved. Biosimilars typically enter the market after the patent protection period of the original drug has expired, providing a more cost-effective treatment ...
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MtoZ Biolabs - Gene Knockout for Drug Screening and Target Identification

MtoZ Biolabs - Gene Knockout for Drug Screening and Target Identification

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
A key step in drug discovery is target identification—identifying "druggable" biological targets. After a target is identified, it must be validated to demonstrate the functional relationship between the target and disease phenotype while ensuring safety. The drug discovery process is lengthy and costly, but good target validation increases the likelihood of developing effective drugs and ...
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MtoZ Biolabs - Urine Eicosanoid Metabolites Analysis Service

MtoZ Biolabs - Urine Eicosanoid Metabolites Analysis Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Prostanoids, also known as eicosanoids, are a family of signaling molecules produced and secreted by various types of cells under both normal and pathological conditions. In the human body, these metabolites are excreted into body fluids such as plasma and urine. The precursors of prostanoids are 20-carbon polyunsaturated fatty acids (PUFAs) like arachidonic acid (C20:4), which are esterified in ...
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