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Medgenome Next Generation Sequencing Services
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Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
It is estimated that there are approximately 1010–1011 B cells in a human adult. A BCR is composed of two identical heavy chains generated by recombination of V, D and J segments and two identical light chains generated by recombination of V and J segments. Human BCRs undergo recombination at these variable regions, generating a large ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
However, identification of all potential clonotypes in a diverse repertoire of TCRs requires sensitive methods of detection. Next-generation sequencing (NGS) technologies have recently enabled accurate detection of TCRs, and in combination with other assays, allow for the assessment of the TCR repertoire in patients which in turn is a proxy for ...