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Brain Blood Product Applications For The Medical Health Care Industry
9 applications found
Kirkstall’s Quasi Vivo® system aims to establish and optimise a human in vitro 3D Blood Brain Barrier (BBB) in an effort to identify important mechanistic pathways for successful biomarker analysis, drug delivery and toxicity ...
ByKirkstall Ltd. based in York, UNITED KINGDOM
The delivery of therapeutical compounds such as RNA drugs into the brain presents the challenges of RNA preservation and the crossing of the blood brain barrier. Exosomes loaded with the specific siRNA sequences and marked with the neuron specific RVG peptide show specific accumulation in neurons, microglia and oligodendrocytes in the brain, effectively reducing genetic expression. This is a potential approach for brain diseases ...
ByNanovex Biotechnologies based in Llanera, SPAIN
The trespassing of the blood brain barrier is a challenge for the treatment of central nervous diseases such as Alzheimer, Parkinson, stroke, or cancer (glioma). ...
ByNanovex Biotechnologies based in Llanera, SPAIN
More than 10 million people worldwide are living with Parkinson’s. Brain tumors and tumors of the central nervous system are the most common form of cancer in children under 19 and the leading cause of cancer-related deaths in children under 14 in the U.S. While antibody drugs have made great strides in cancer therapies, crossing the blood-brain barrier (BBB) and ensuring proper clearance from the brain have hindered the use of antibody ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
A cerebral aneurysm is a weakened part of an artery in the brain that bulges and fills with blood. When it ruptures, blood spills into the surrounding brain tissue resulting in a hemorrhagic ...
ByArtio Medical, Inc. based in Prairie Village, KANSAS (USA)
This is particularly true for traumatic brain injury patients. Standard methods of blood infusion are often too slow, particularly when vascular access is limited to smaller-gauge IV’s or IO. ...
By410 Medical based in Durham, NORTH CAROLINA (USA)
As targeted therapies evolve and the limitations of antibody-based therapies become clearer, a growing number of research teams are exploring the therapeutic potential of ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
In many therapeutic areas, current treatments involve significant side effects. Combining drug compounds with affinity agents that target specific cell surface receptors can dramatically reduce off-target effects and improve treatment effectiveness. In several studies, aptamer-mediated drug delivery has reduced toxicity and improved drug performance. ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
This system is instrumental for transcranial ultrasound localization microscopy (ULM), allowing for the imaging of the brain's microvasculature at a microscopic resolution, which is particularly beneficial for diagnosing and monitoring stroke and aneurysm. The system's current projects, in collaboration with entities like Geneva University and Physics for Medicine Paris, include developing transcranial ULM scanners for adults and creating implantable probes capable of continuous cerebral ...
ByIconeus based in Paris, FRANCE