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Immune Response Product Applications For The Medical Health Care Industry
18 applications found
Determining adverse immune responses to monoclonal ...
ByAlcyomics Ltd. based in Newcastle Upon Tyne, UNITED KINGDOM
Natural killer (NK) cells have long been known to play a significant role in the body’s innate immune response. They were first described in the 1970s, but only in the last 15 years has significant progress been made in understanding the complexities and therapeutic potential these cells offer in helping fight cancer and other diseases. Today, we know that NK cells not only detect and identify malignant cancer cells, but they also induce cancer cell death and even help ...
ByKiadis Pharma NV based in Amsterdam, NETHERLANDS
No single preventive health intervention is more cost-effective than immunization. Immune repertoire analysis has taken a predominant role in the development of vaccination strategies against infectious disease and has enabled characterization of the immune response against pathogens at high ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Dysregulation of immune cell functions can result in many serious and fatal diseases that require re-modulating the immune cells and restoring their normal response. Monitoring of immune cells while interacting with self-cells, pathogens, and cancer promotes our understanding of immune response or its failure ...
ByTelight based in Brno, CZECH REPUBLIC
Downregulating the immune response is necessary for the treatment of autoimmune diseases. In this aspect, the APO2L/TRAIL ligand is a key intermediate in immune cascades and is secreted in exosomes in natural conditions. Its alteration has been associated with rheumatoid arthritis. ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Our multi-targeted approach involves improving epithelial cell homeostasis, restoring appropriate immune responses, and repairing secretory cell ...
ByKallyope Inc. based in New York City, NEW YORK (USA)
In the tumor microenvironment, IFN-α exerts its anti-tumor activity both directly by promoting cancer cell apoptosis and inhibiting vascularization and indirectly by restoring anti-tumor immune response. Temferon™ turns TEMs into a “Trojan Horse” to release IFN-α inside tumors, rebuilding the immune system and counteracting cancer ...
ByGenenta Science based in Milano, ITALY
The increase or decrease of a natural immune response to obtain a therapeutic result is the basis of immunotherapy. ...
ByNanovex Biotechnologies based in Llanera, SPAIN
High-throughput analysis of immune repertoires has contributed to the elucidation of mechanistic underpinnings of autoimmunity, driving the development of novel therapies and better ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Inside the hyperbaric chamber, a user will absorb oxygen close to four times the normal breathing ...
ByOXYHELP INDUSTRY based in Bucuresti, ROMANIA
Longitudinal imaging of pancreatic cancer. Monitor in a minimally invasive manner both tissue morphology and fibrosis (fluorescein) and cathepsin activity (Prosense® 680). A very thin probe (S 650) was used to monitor the pancreas of the same mouse over 9 months. ...
ByMauna Kea Technologies based in Paris, FRANCE
Influenza, commonly known as “the flu”, is an infectious disease caused by an influenza virus that is spread by droplet transmission through the air from coughs and sneezes or by touching surfaces contaminated with the virus. Symptoms can be mild to severe with the most common including a high fever, runny nose, sore throat, muscle pains, headache, coughing, and feeling tired. These symptoms typically begin two days after exposure to the virus and most last less than a week. More severe complications ...
ByFluGen, Inc. based in Madison, WISCONSIN (USA)
2A Pharma’s vaccine platform is based on mutated parvoviral particles consisting essentially of one protein. The particles contain no viral genome and are replicative defective and non-pathogenic. The particle capsid surface has repetitive, immunogenic sites, where peptides of interest can be inserted and allows us to generate monovalent or bivalent vaccines as required. Each peptide of interest will be presented 60 times on the capsid surface and both the innate and adaptive immune systems are activated to ...
By2A Pharma ApS based in Aalborg Øst, DENMARK
Aptamers are short strands of DNA or RNA with unique secondary and tertiary structures that enable highly selective binding to various types of targets. While aptamers are similar to antibodies in their ability to specifically bind with high affinity, there are some key differences between antibodies and aptamers which have prompted an increase in aptamer development projects. Several hot areas for aptamers, along with specific aptamer advantages, are outlined below. ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
As targeted therapies evolve and the limitations of antibody-based therapies become clearer, a growing number of research teams are exploring the therapeutic potential of ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
Monoclonal antibodies (mAbs) are used to treat patients in a variety of conditions such as infectious disease, cancer, and autoimmunity. Discovery of therapeutic antibodies is a laborious process, that depends on high-throughput screening of antibody candidates to determine antigen specificity. Immune repertoire analysis provides accurate, sensitive, and rapid detection of antibody sequences in panning rounds or exposured animal models, accelerating the discovery of ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Increase clinical translation with Organ-Chips for ADME-Tox assessments. Accurate ADME-Tox profiling of preclinical drug candidates remains a challenge. Preclinical ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicity) studies are pivotal to predicting human response. However, approximately 30% of drugs fail during human clinical trials due to adverse reactions despite promising preclinical study results, and another 60% fail due to lack of efficacy. As companies broaden the modality toolbox ...
ByEmulate based in Boston, MASSACHUSETTS (USA)
More than 5 million people in the United States and an estimated 50 million people worldwide are living with Alzheimer’s disease. More than 10 million people worldwide are living with Parkinson’s. Brain tumors and tumors of the central nervous system are the most common form of cancer in children under 19 and the leading cause of cancer-related deaths in children under 14 in the U.S. While antibody drugs have made great strides in cancer therapies, crossing the blood-brain barrier (BBB) and ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)