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Medical diagnostics solutions for colorectal cancer sector - Medical / Health Care

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Colorectal cancer (CRC) is the third most common cancer all over the world. About 1.8 million new CRC cases were diagnosed globally in 2018, mostly in developed countries. The incidence of colorectal cancer is increasing in line with the ageing population.  Early detection is key to successful treatment of the disease and related cost management. An efficient screening strategy is essential to detect the disease early, when it often does not produce symptoms. The currently available faecal occult blood test (FOBT) and faecal immunochemical test (FIT) are safe and inexpensive, but test sensitivities are limited, and the required stool collection is inconvenient. Screening colonoscopies are popular in the US, but they are expensive to perform, extremely invasive and can sometimes cause serious complications.

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The DiagNodus approach to the CRC detection is based upon measuring CRC biomarkers captured on a swab device self-applied by the patient. The adoption of the approach would still require confirmatory diagnostic colonoscopies, but CRC detection rate should be considerably improved and numbers of unnecessary colonoscopies dramatically reduced.

DiagNodus has successfully completed its first clinical study targeting CRC in 2018, and is ready to develop a new commercial product for CRC detection.

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