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Nutlin-3a - Chemical & Pharmaceuticals
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BOC Sciences is committed to supplying cost-effective products and services. We provide Nutlin-3a (Cas No:675576-98-4). More information, please visit the website: http://www.bocsci.com/nutlin-3a-cas-675576-98-4-item-84-425358.html
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Nutlin-3a is an inhibitor of MDM2 (human homolog of murine double minute 2), which disrupts its interaction with p53, leading to the stabilization and activation of p53. Nutlin-3a activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression of MDM2 protein.
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