Alpha Interferon Articles & Analysis: This-Year
1 articles found
Prolonged Half-Life PEGylation increases hydrodynamic volume, preventing rapid kidney filtration and extending plasma half-life. For example, PEGylated interferon-α (Pegasys® and PegIntron®) shows a 5-10-fold longer half-life than its non-PEGylated counterpart, allowing weekly dosing instead of daily injections. 2. ...