Chronic Kidney Failure Articles & Analysis
16 articles found
Matrix Gla Protein (MGP) is a small, vitamin K-dependent extracellular matrix protein that plays a critical role in the regulation of vascular calcification and bone development. As a natural inhibitor of pathological mineralization, MGP has attracted significant attention in cardiovascular and skeletal biology research. The development of recombinant MGP protein has enabled researchers to study ...
Any disruption in this system can lead to conditions such as hypertension, atherosclerosis, and heart failure. Research in cardiovascular biology aims to unravel the underlying causes of these diseases and improve therapeutic interventions. ...
Structure of Matrix Metalloproteinase (MMP) Family In vertebrates, the MMP family consists of 28 members, at least 23 of which are expressed in human tissues, 14 of which are expressed in the vascular system. MMPs are usually classified into collagenases, gelatinases, stromelysins, matrilysins, membrane-type (MT)-MMPs, and other MMPs based on their substrates and the organization of their ...
GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple guidelines as appropriate initial treatment for type 2 diabetes patients with atherosclerotic cardiovascular disease (ASCVD) or those at high risk for ASCVD, heart failure and/or chronic kidney ...
These include: Atrial fibrillation (Afib) Coronary artery disease Diabetes High blood pressure (hypertension) Obstructive sleep apnea (OSA) Obesity Chronic kidney disease Amyloidosis or other infiltrative heart diseases What are the symptoms of diastolic heart failure? Diastolic heart failure has many of the same ...
Muscle loss / muscle wasting is the condition in which, proteolytic systems for protein degradation are activated, while protein synthesis decreases, thereby resulting in muscle fiber shrinkage. This condition may be due age or might be due some chronic conditions like Diabetes mellitus (DM) or chronic kidney disease (CKD). Extreme muscle wasting often results in weight loss. Such a condition is ...
Mice have long served as the species of interest for biomedical research thanks to their genetic, physiological, and anatomical similarity to humans. Mice kidney samples are used to study renal biology covering topics such as acute kidney injury to chronic kidney disease, both of which are extremely useful for better ...
As we begin this New Year we have an opportunity to begin with a fresh start as we pursue our passion to promote and speed the healing of wounds! Our role as Wound Care Clinicians has risen to a whole new level of essential care for an extremely high risk population. In this current Covid-19 climate that we are living in, we are all facing challenges that we have never dealt with before. ...
Around 37 million people in the United States and around 700 million people worldwide have chronic kidney disease which require patients to utilize dialysis centers. ...
They may have a lot of comorbidities—such as diabetes, chronic kidney disease, end-stage renal disease—and they’re complex cases. ...
After seven years and 5,300-patients tested, the results of the landmark TAILOR-PCI trial were announced in a virtual ACC session. This trial investigated whether a prospective approach using rapid on-site CYP2C19 testing could improve patient outcomes when selecting P2Y12 inhibitor therapy following PCI procedure. This is based on the well-established evidence that approximately 30-50% of ...
And now to a story that is never far from the headlines. If is about an EPA – Registered herbicide that has been linked to kidney disease. This story demonstrates the extent that entities will go to protext their commercial interests. The story comes from the organisation Beyond Pesticides. (Beyond Pesticides, February 6, 2019) The American Association for the Advancement of Science (AAAS) ...
The use of a novel implantable string subcutaneous defibrillator (ISSD, Newpace) that has no can, and has been designed to be placed without the need for a surgical pocket, may allow improved patient compliance and aesthetics, is less invasive, and has optimal implantation time. The results from a first-in-man feasibility study on subcutaneous defibrillation utilising an integrated flexible ...
A rigorous and consistent set of outcomes definitions for hemodialysis access are necessary to clarify factors contributing to fistula success and the clinical consequence of fistula failure. Keywords: Arteriovenous fistula, Haemodialysis, Patency, Maturation, Meta-analysis Introduction The use of chronic haemodialysis (HD) as renal replacement therapy (RRT) ...
This case study discusses hospital readmissions and provides healthcare professionals with recommended medical algorithms in the form of scores, models, and calculators that can aid in reducing readmissions, especially when related to antibiotic resistant microbiological pathogens. When health analytics, such as the CDC antibiotic resistance program and other algorithms are integrated into ...
If you think it’s hard to get HVAC money for schools and similar public buildings, there is a harder nut to crack: correctional facilities. It can be even more difficult to get additional funds appropriated to improve conditions in buildings where people are incarcerated. Compounding the problem, many correctional facility employees are in close proximity with the inmate community daily. ...
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