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Chronic Lymphocytic Leukemia Articles & Analysis: This-Year

1 articles found

Understanding the BCL2 Gene Family: Function, Research Highlights, and Medical Relevance

Understanding the BCL2 Gene Family: Function, Research Highlights, and Medical Relevance

A major breakthrough occurred with the FDA approval of Venetoclax (ABT-199), a BCL2-selective inhibitor used in the treatment of chronic lymphocytic leukemia (CLL). Venetoclax works by mimicking BH3-only proteins, thereby displacing pro-survival BCL2 proteins and triggering apoptosis in cancer cells. In 2020, a study published in the New ...

ByCreative BioMart

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