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Drug Discovery Articles & Analysis: Older
139 articles found
Pharmaceutical Development: These cell lines are essential in the drug discovery pipeline, allowing for high-throughput screening and functional assays to evaluate drug efficacy and safety. ...
Understanding the complex world of drug discovery and development necessitates familiarity with key players in cellular communication. ...
This process also aids in screening for monoclonal antibodies with high specificity and affinity, crucial for therapeutic applications in oncology, infectious diseases, and autoimmune disorders. 4. Glycan-Based Drug Discovery The study of glycan structures has led to the discovery of novel drug candidates targeting ...
This technology has revolutionized various fields, including drug discovery, gene expression studies, and cellular signaling research. ...
Alfa Cytology has introduced its advanced drug development services for brain tumors. Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the intricacies and unique challenges associated with brain ...
Technological advancements and innovative research have continuously led to the discovery and development of new methodologies in the field of biological and medical sciences. One such breakthrough discovery is bacterial genome editing, which opens a new world of opportunities and challenges in the field of biotechnology and genomics. ...
A wide range of assays can be performed in this model, from target discovery, target validation or toxicology studies to tumor generation for corresponding in vivo efficacy testing. ...
The scientific community’s concerted efforts in further refining these technologies and their applications can transform our approach to disease modeling, drug discovery, and therapeutic development. In conclusion, zebrafish genome editing services demonstrate immense promise as robust platforms for genomic research. ...
Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...
Functions of PeptidomimeticsPeptidomimetics have a wide range of functions and are being increasingly explored in drug discovery and development because of their potential therapeutic benefits. ...
Furthermore, AI-driven platforms have the ability to streamline drug discovery and development processes, by simulating interactions between drugs and genetic targets, predicting potential side effects, and identifying optimal dosage regimens. ...
Immortalized cell lines are valuable tools in biological research and drug discovery, as they provide a continuous and stable cell population for experimental studies. ...
Immune checkpoints, such as PD-1 and CTLA-4, play a critical role in regulating the balance between activating and inhibitory signals in the immune system, while Toll-like receptors are involved in recognizing conserved molecular patterns present on pathogens and activating the immune response. In immunological research and drug discovery, it is essential to ...
Applications: Research: Mapping the architecture and alterations in the cytoskeleton in various diseases. Drug Discovery: Observing how pharmaceuticals affect cytoskeletal integrity. ...
Natural product extraction is also important in the development of new drugs and pharmaceuticals. Many drugs on the market today are derived from natural sources or inspired by natural compounds. Extracting bioactive compounds from natural sources allows researchers to study their properties and potential applications in drug ...
Conditional knockout cell lines provide better control of gene expression and provide a more physiologically relevant model for studying the role of target genes and drug discovery. Recently, with the development of the CRISPR/Cas9 gene editing technology, it has become possible to use this technique to generate conditional knockout cell lines. ...
This information aids in understanding the drug's mechanism of action and optimizing drug design.3. Optimization of Drug Formulations and Drug Delivery SystemsCD technology can help analyze conformational changes of drug molecules in different formulations, or their encapsulation status in carrier systems (such ...
DIA technology has a wide range of applications in biomedical research, disease biomarker discovery, and drug development.DIA Proteomics SequencingDIA technology systematically scans the entire mass range during mass spectrometry analysis, rather than analyzing only a few preselected ions. ...
Oncology drug development makes up almost half of the annual R&D expenditure of biopharmaceutical companies. ...
Furthermore, AI-driven platforms have the ability to streamline drug discovery and development processes, by simulating interactions between drugs and genetic targets, predicting potential side effects, and identifying optimal dosage regimens. ...