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Drug Discovery Articles & Analysis: This-Year
18 articles found
This transformation enables them to differentiate into any cell type, offering significant potential for disease modeling, drug discovery, and therapeutic applications. However, proper characterization of iPSCs is critical to ensuring their utility and safety in research and clinical settings. ...
Moreover, in model organism studies, CRISPR/Cas9 lentiviral systems are employed to create stable cell lines or animal models that replicate human diseases, facilitating drug discovery and therapeutic development. Conclusion The CRISPR/Cas9 lentivirus production service represents a crucial advancement in gene editing technology, offering researchers a potent ...
In the realm of drug discovery, kinase screening services have emerged as a pivotal tool for understanding complex cellular signaling pathways and identifying potential therapeutic targets. ...
In this white paper, Predictive Oncology (POAI) highlights a recent successful project in partnership with the University of Michigan Natural Products Discovery Core (NPDC) through the ACE program. The ACE program supports academic researchers in their early drug discovery and development initiatives by providing access to the POAI ...
Alfa Cytology shows its determination to turn scientific discoveries into workable solutions through its broad range of development services that target FAP. ...
In the realm of pharmacology and drug development, the assessment of drug permeability is essential. One of the most widely recognized in vitro models for evaluating the intestinal absorption of compounds is the Caco-2 permeability assay. ...
In our last blog, Peter discussed how AI is accelerating the drug discovery process and putting pressure on chemists, who must find ways of developing these potential drugs for subsequent testing or production. ...
ByBUCHI
Understanding the metabolic stability of potential drug candidates is paramount in the realm of pharmaceutical development. ...
Alfa Cytology has officially released its antibody-drug conjugates(ADCs) development services which demonstrates the dedication to fighting cancer through advanced treatment methods. ...
Creative Bioarray establishes itself as a world leader in life science innovation through its complete range of organoid services that enhance drug discovery, disease modeling, and personalized medicine. Our advanced system delivers high-quality, reproducible organoids to researchers, enabling significant advancements in their scientific work. ...
In the realm of drug discovery, the search for innovative therapies often leads to new paradigms. ...
This knowledge can help to identify new targets for drug development and understand the genetic basis of diseases. Disease Modeling: Custom knockout cell lines can mimic specific diseases by disabling genes associated with particular disorders. This modeling can be invaluable for studying the pathophysiology of diseases such as cancer, neurodegenerative disorders, and metabolic ...
Preclinical drug discovery represents a critical phase in the development of new therapeutics. ...
In addition, the advent of diverse drug discovery solutions has unveiled immense possibilities for identifying novel therapeutic targets and crafting personalized therapies. ...
These services include developing targeted therapies, immunotherapy, and inhibitors and drugs. Each stage must undergo rigorous quality testing to achieve the highest safety standards. ...
Additionally, multiplex cytokine analysis is a valuable tool in vaccine development and drug discovery, providing real-time feedback on immune modulation. ...
Pharmaceutical Research: Identifying bioactive glucosinolate metabolites can aid in drug discovery and the development of nutraceuticals. Creative Proteomics’ expertise in targeted metabolomics ensures that researchers can obtain reliable and reproducible results for their glucosinolate studies. ...
High-throughput screening (HTS) has become a cornerstone of drug discovery, allowing researchers to rapidly test thousands of compounds for their ability to activate or inhibit specific nuclear receptors. ...