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Drug Interaction Articles & Analysis: This-Year
6 articles found
In biotechnology and agriculture, analyzing sterols can help in developing new drugs or engineering more resilient crops. Therefore, a robust Sterol Lipids Analysis service is an indispensable tool for researchers, clinicians, and drug developers. ...
This article explores the mechanisms, benefits, challenges, and future prospects of PEGylation in drug development. Mechanism of PEGylation PEGylation involves the covalent or non-covalent attachment of PEG—a synthetic, hydrophilic polymer—to a drug molecule. ...
This article delves into the application of nitrogen compounds in antibiotic research and development, illustrating how they influence antibiotic efficac Fundamental Properties of Nitrogen Compounds Nitrogen compounds are defined as chemical substances containing nitrogen atoms within their molecular structure. In drug chemistry, these compounds are renowned for their diverse ...
Conversely, low metabolic stability can lead to rapid clearance from the system, necessitating modifications in the chemical structure to enhance the drug’s longevity. Moreover, S9 assays help in predicting drug-drug interactions. Many drugs are metabolized by the same pathways; thus, understanding the ...
This diversity allows for the metabolism of a wide range of compounds, influencing the pharmacological effects and toxicity of drugs. Role in Drug Metabolism The role of cytochrome P450 in drug metabolism is two-fold: it can either detoxify drugs or convert them into active metabolites. The metabolic pathways involving CYP ...
Additionally, in silico screening techniques, such as molecular docking, have become invaluable tools in predicting how potential drugs may interact with nuclear receptors at a molecular level. These computational methods can significantly reduce the time and resources needed in the early stages of drug development. ...