End Stage Kidney Disease Articles & Analysis
9 articles found
GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple guidelines as appropriate initial treatment for type 2 diabetes patients with atherosclerotic cardiovascular disease (ASCVD) or those at high risk for ASCVD, heart failure and/or chronic kidney ...
Failure of Medical Therapy in ADHF: an Ode to the Kidneys The pathophysiology of fluid retention in ADHF in patients with advanced disease has been detailed previously (Figure 2A).21 In brief, reduced circulating blood pressure and cardiac output due to impaired contractility activates baroceptors, stimulates the renin-angiotensin-aldosterone system, and ...
Abstract : Intimal hyperplasia is one of the prominent failure mechanisms for arteriovenous fistulas and arteriovenous access grafts. Human tissue-engineered vascular grafts (TEVGs) were implanted as arteriovenous grafts in a novel baboon model. Ultrasound was used to monitor flow rates and vascular diameters throughout the study. Intimal hyperplasia in the outflow vein of TEVGs was assessed at ...
Background: Synthetic expanded polytetrafluorethylene (ePTFE) grafts are routinely used for vascular repair and reconstruction but prone to sustained bacterial infections. Investigational bioengineered human acellular vessels (HAVs) have shown clinical success and may confer lower susceptibility to infection. Here we directly compared the susceptibility of ePTFE grafts and HAV to bacterial ...
Objective: Patients with end stage renal failure who require haemodialysis suffer morbidity and mortality due to vascular access. Bioengineered human acellular vessels (HAVs) may provide a haemodialysis access option with fewer complications than other grafts. In a prospective phase II trial from 2012 to 2014 (NCT01744418), HAVs were implanted into 40 haemodialysis patients at three sites in ...
October 6, 2021—Surendra Shenoy, MD, presented findings from a first-in-human (FIH) evaluation of the Amplifi vein dilation system (Artio Medical, Inc.), which is a small, wearable blood pump device that dilates arm veins before arteriovenous fistula (AVF) creation. Amplifi is designed to improve AVF eligibility, reduce maturation failure, reduce time to maturation, and prolong primary ...
They may have a lot of comorbidities—such as diabetes, chronic kidney disease, end-stage renal disease—and they’re complex cases. ...
Keywords Vascular access · Hemodialysis · Healthcare costs · Health economics · Arteriovenous fistula · Arteriovenous graft Abstract Introduction: Hemodialysis (HD) in end-stage renal disease (ESRD) patients requires vascular access (VA) through an arteriovenous fistula (AVF), a prosthetic arteriovenous ...
Keywords: Arteriovenous fistula, Haemodialysis, Patency, Maturation, Meta-analysis Introduction The use of chronic haemodialysis (HD) as renal replacement therapy (RRT) in patients with end stage renal disease (ESRD) is a prevalent practice worldwide and in the USA, and HD accounts for approximately 63% of RRT.1 The US Renal Data System ...