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Inflammation Tissue Articles & Analysis: Older

13 articles found

Development of Nanobody-Based Drug Delivery Systems

Development of Nanobody-Based Drug Delivery Systems

One of the key advantages of nanobodies is their small size, which allows them to penetrate tissues more effectively than conventional antibodies. They also have a high degree of stability and solubility, making them suitable for various routes of administration. ...

ByBOC Sciences


Cytokines: The Master Regulators of Immunity and Inflammation

Cytokines: The Master Regulators of Immunity and Inflammation

Their primary roles include: Immune Regulation: Cytokines orchestrate the complex interplay of immune cells during infection, inflammation, and tissue repair. They activate immune cells, stimulate their proliferation and differentiation, and promote their migration to target sites. Inflammatory Response: Cytokines play a central role in the initiation and ...

ByCreative BioMart


What is Sepsis? Key Symptoms, Potential Complications, and Vital Treatment

What is Sepsis? Key Symptoms, Potential Complications, and Vital Treatment

When a person suffers from sepsis, his or her immune system has been triggered in response to an infection, which causes inflammation and damages tissues in the body. Symptoms of Sepsis The symptoms of sepsis may include: Fever (102 degrees Fahrenheit or higher) Chills Rapid breathing (above 20 breaths per minute) or respiratory rate above 30 breaths per ...

ByAmbient Clinical Analytics


A new perspective regarding laser therapy

A new perspective regarding laser therapy

Similarly, the compression of the spinal cord and nerve roots by disc disease and degenerative osteoarthritis are rapidly relieved by the reduction of inflammation, scar tissue formation and osteophyte resorption, resulting in the disappearance of the symptomatology commonly referred to as radiculitis/sciatica. ...

ByMedical Quant


Discovery of Bispecific Antibodies and Immune Checkpoint Inhibitors That Kill Glioblastoma Cells and Melanoma Cells, and Block the Metastasis of Malignant Melanoma Cells to the Lung by Over 90%

Discovery of Bispecific Antibodies and Immune Checkpoint Inhibitors That Kill Glioblastoma Cells and Melanoma Cells, and Block the Metastasis of Malignant Melanoma Cells to the Lung by Over 90%

Chitinase 3-like-1 (CHI3L1) is a member of the 18 glycosyl hydrolase gene family that is readily detected in the circulation of normal individuals and expressed at exaggerated levels in the circulation of individuals with diseases characterized by inflammation, tissue remodeling and or cancers. Discoveries Recent studies from our laboratory have demonstrated ...

ByOcean Biomedical


VetStem Cell Therapy for Canine Cruciate Ligament Tears

VetStem Cell Therapy for Canine Cruciate Ligament Tears

Cruciate ligament rupture is one of the most common reasons for hind limb lameness, pain, and subsequent knee arthritis in dogs. Additionally, according to the American College of Veterinary Surgeons, 40-60% of dogs who injure one cruciate ligament will go on to injure the other cruciate ligament in the future. While there are multiple treatment options available, both surgical and non-surgical, ...

ByVetStem Biopharma


Q&A with Dr. Veronica Iatarola Antas, Research Scientist and Project Lead at Regeneus

Q&A with Dr. Veronica Iatarola Antas, Research Scientist and Project Lead at Regeneus

Regeneus has two competitive, proprietary platforms (Progenza™ and Sygenus) that target pain and inflammation, while promoting tissue repair. The disease modifying properties of these two products, due to our patented inclusion of Mesenchymal Signalling Cells (MSCs) and their bioactive molecules (‘secretome’), make them superior to most ...

ByRegeneus Ltd.


Q&A with Prof. Graham Vesey PhD, Chief Scientific Officer and Executive Director at Regeneus

Q&A with Prof. Graham Vesey PhD, Chief Scientific Officer and Executive Director at Regeneus

Our lead platform technology Progenza™ contains both MSCs and their bioactive secretome for an ideal therapeutic effect that treats symptoms of pain and inflammation and also promotes tissue repair. Our second technology platform, Sygenus, utilises the bioactive secretome of MSCs only, and works as a topical treatment for pain and ...

ByRegeneus Ltd.


Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

Here, we show that compared with smoke exposure, mice receiving ENDS vapor for 4 months failed to develop pulmonary inflammation or emphysema. However, ENDS exposure, independent of nicotine, altered lung lipid homeostasis in alveolar macrophages and epithelial cells. ...

ByJohnson Controls, Inc.


Cryotherapy - Baby It’s Cold Inside

Cryotherapy - Baby It’s Cold Inside

Modern cryotherapy (which comes from the Greek kyro, meaning “cold” and therapeia, meaning “healing”) can be traced back thousands of years, and some form of it was practiced by the ancient Greeks, Romans, and Egyptians, among other civilizations, which used extreme cold therapy to treat injuries and reduce inflammation. In 1978, a Japanese ...

ByPureAire Monitoring Systems, Inc


Oxygen therapy for rheumatology

Oxygen therapy for rheumatology

As an autoimmune disorder, rheumatoid arthritis develops when the immune system starts wrongly attacking its own body’s tissues. The process of inflammation involves soft tissues – tendons, ligaments and muscle, also it can affect the bone. Joint tissues (synovial membranes) swell up, there is disturbance in blood ...

ByOXYHELP INDUSTRY


	 Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis

Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis

Publication Summary: Compound induced chronic liver injury can lead to initiation of profibrotic processes resulting in sustained production of growth factors and profibrotic cytokines where inflammation, tissue remodeling and repair pathways are activated simultaneously to counteract the injury. ...

ByOrganovo Holdings Inc.


Induction of adipose tissue regeneration by chemically-modified hyaluronic acid

Induction of adipose tissue regeneration by chemically-modified hyaluronic acid

Standard histology and immunohistochemistry demonstrated low levels of inflammation at all time periods, absence of any fibrous capsule coupled with the presence of mature adipocytes within the degrading gel. It is concluded that the chemical architecture of HYADD3 gel causes the de novo regeneration of soft tissue by recruitment of appropriate progenitor ...

ByInderscience Publishers

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