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Patient Loading Articles & Analysis: Older

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Combination of two epitope identification techniques enables the rational design of soy allergen Gly m 4 mutants

Combination of two epitope identification techniques enables the rational design of soy allergen Gly m 4 mutants

In ELISA, the binding of the mutant allergens to polyclonal rabbit-anti Gly m 4 serum as well as IgE purified from Gly m 4-reactive soybean allergy patient sera is reduced by up to 63% compared to the wild-type allergen. Basophil stimulation experiments using RBL-SX38 cells loaded with patient IgE are showed a decreased stimulation from 25% for ...

ByLenioBio GmbH

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