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Pediatry Articles & Analysis

63 articles found

Common Types of Excipients in Pharmaceutical Formulations

Common Types of Excipients in Pharmaceutical Formulations

In the pharmaceutical industry, excipients play a crucial role in the formulation of medicines. These inactive substances, which are combined with the active pharmaceutical ingredient (API), perform various functions that enhance the effectiveness, stability, and overall performance of drug products. Understanding the common types of excipients is essential for pharmaceutical scientists and ...

ByBOC Sciences


Hydrogen and Methane Breath Testing in Children: A Practical Guide

Hydrogen and Methane Breath Testing in Children: A Practical Guide

Hydrogen and methane breath testing (HMBT) is a non-invasive diagnostic tool frequently used to assess small intestinal bacterial overgrowth (SIBO) and carbohydrate malabsorption disorders such as lactose and fructose intolerance. Despite its widespread use in adults, its application in children is less standardised, and clinicians often face uncertainties about adapting adult protocols for the ...

ByBedfont Scientific Limited


New NICE Guidelines for Asthma: FeNO Testing and the NObreath® Device in Adult and Paediatric Care

New NICE Guidelines for Asthma: FeNO Testing and the NObreath® Device in Adult and Paediatric Care

On Wednesday, 27th November, the National Institute for Health and Care Excellence (NICE), the British Thoracic Society (BTS), and the Scottish Intercollegiate Guidelines Network (SIGN) updated and published a joint guideline on asthma diagnosis, monitoring, and chronic asthma management. Streamlining asthma management BTS/SIGN and NICE published guidelines independent of each other. To align ...

ByBedfont Scientific Limited


When is It Necessary to Develop an Oral Liquid Formulation?

When is It Necessary to Develop an Oral Liquid Formulation?

In the ever-evolving world of pharmaceutical development, the quest to innovate and improve the delivery of drug substances remains a top priority. Among the many formulation strategies, oral liquid formulations hold a special place, offering alternatives particularly appealing for specific populations and addressing unique formulation challenges. The Necessity of Oral Liquid Formulations ...

ByCD Formulation


Customer Spotlight: Laboratory of Genetics and Genomics, Cagliari

Customer Spotlight: Laboratory of Genetics and Genomics, Cagliari

We recently spoke with Manuela Badiali, Rita Congiu, and Stefania Murru from the Laboratory of Genetics and Genomics, Microcitemico Pediatric Hospital – A. Cao, Cagliari, about how SOPHiA DDM™ RNAtarget Technology has helped them optimize their variant analysis workflow. ...

BySOPHiA Genetics


Addressing Primary Care Challenges with the NObreath®

Addressing Primary Care Challenges with the NObreath®

FeNO Testing in Asthma Care Although airway eosinophilic inflammation is a key characteristic of asthma, there are few methods available to measure it. This inflammation can be assessed by measuring eosinophils and eosinophilic cationic protein (ECP) in sputum or by measuring ECP in blood samples1. However, these methods are considered time-consuming, expensive, and not readily available. For ...

ByBedfont Scientific Limited


Article on Identification of Pediatric Brain Tumors

Article on Identification of Pediatric Brain Tumors

An article on the rapid identification of pediatric brain tumors using DMS was published in Frontiers in Oncology, section Neuro-Oncology and Neurosurgical Oncology! The results show that most common pediatric brain tumor samples can be differentiated with DMS. DMS shows promise in becoming and additional instrument for real-time diagnosis of brain tumors. (The header image for this post ...

ByOlfactomics


Understanding the Different Levels of CPR Training

Understanding the Different Levels of CPR Training

CPR training is more than just a certification; it’s a crucial skill that can save lives in critical situations. In Kentucky, where industries range from manufacturing to healthcare, the demand for comprehensive CPR and first aid training is ever-present. The different levels of CPR training are designed to meet specific needs – from basic techniques for laypersons to advanced ...

ByRescue Solutions LLC


How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...

ByCreative Bioarray


How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study

Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...

ByCreative Bioarray


API - Oseltamivir Phosphate

API - Oseltamivir Phosphate

Introduction Oseltamivir phosphate is a white or almost white crystalline powder with the chemical name ethyl(3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-cyclohex-1-ene-1-carboxylate phosphate. It is an influenza viral neuraminidase inhibitor used in the prevention and treatment of influenza. Application in the treatment of influenza Introduction of influenza Influenza, also called flu or ...

ByAlfa Chemistry


Inflammation, Immunity and Cancer

Inflammation, Immunity and Cancer

Relationship Between Immunity, Inflammation and Cancer Immunity is an act of self-protection of the body. The immune response is divided into specific and non-specific. The antigen and antibody responses are generally referred to as specific immune responses, which require the participation of B cells and T cells. Other immune cells such as macrophages and NK cells mediate non-specific immune ...

ByCreative Proteomics


IPEG 2023: Setting a Foundation for Healthcare Transformation

IPEG 2023: Setting a Foundation for Healthcare Transformation

I recently had the pleasure of attending the IPEG annual meeting in Sorrento, Italy. The collegiality of the surgeons attending the conference was fantastic, and the views of Sorrento and the Island of Capri were stunning. With smaller accessible markets (due to smaller patient volumes and higher incidence of rare disease), specialty areas like pediatrics have been overlooked and under-addressed ...

ByCaresyntax


Application of Whole Plasmid Sequencing in Analyzing Drug Resistance Genes of Klebsiella pneumoniae

Application of Whole Plasmid Sequencing in Analyzing Drug Resistance Genes of Klebsiella pneumoniae

Klebsiella pneumoniae is a significant causative agent of hospital- and community-acquired infections, presenting with various clinical manifestations. Notably, the rapid spread of carbapenem-resistant K. pneumoniae (CRKP) has become a global threat, leading to high morbidity and mortality rates. In this context, researchers have employed high-throughput sequencing to investigate drug resistance ...

ByCD Genomics


Do you really have to sacrifice MRI image quality for speed?

Do you really have to sacrifice MRI image quality for speed?

To understand the significance of the SpinTech MRI STAGE software platform, it helps to begin by asking a question: Given that MRI is an incredibly powerful diagnostic tool for neurological diseases like Alzheimer’s, dementia, Parkinson’s and multiple sclerosis (MS), why have radiologists and neurologists had to choose between conducting faster MRI exams and obtaining higher-quality ...

BySpinTech, Inc.


No-touch Forehead Temperature Measurement in Two Clinical Settings

No-touch Forehead Temperature Measurement in Two Clinical Settings

Background. Healthcare personnel prefer devices that maximize efficiency while minimizing cross-contamination as well as cost. The Caregiver® (Thermomedics, Inc., Miami. FL), a new infrared non-contact forehead thermometer has been developed for clinical professional use. Our objective was to evaluate the clinical accuracy and repeatability of the Caregiver as compared to measurements ...

ByThermomedics, Inc.


Luna’s Story: Teen Trailblazer Becomes First BEAR Implant Patient in Connecticut

Luna’s Story: Teen Trailblazer Becomes First BEAR Implant Patient in Connecticut

Very rarely does a high school student who aspires to study medicine get a first-hand opportunity to be a medical trailblazer. But 15-year-old Luna Martini stepped comfortably into that role when she became the first patient in Connecticut to receive a BEAR® Implant to treat her torn anterior cruciate ligament (ACL). A freshman at Farmington High School, Luna aspires to be a doctor herself ...

ByMiach Orthopaedics, Inc.


Solutions Built to Cure - Case study

Solutions Built to Cure - Case study

Whether you are a physiotherapist who is treating a patient or someone who would like to receive rehabilitation safely at home, BECURE is ready to help you. The Problem Physiotherapy (physical therapy) is used for the rehabilitation of neurological, orthopedic, pediatric, geriatric, and rheumatologic diseases; to diagnose muscle-skeletal system diseases; and to treat them. It is a holistic ...

ByBeCure


FluGen Announces Completion of First Cohort in Age De-escalation Clinical Trial of M2SR Flu Vaccine Candidate in Pediatric Subjects Ages 6 Months to 17 Years

FluGen Announces Completion of First Cohort in Age De-escalation Clinical Trial of M2SR Flu Vaccine Candidate in Pediatric Subjects Ages 6 Months to 17 Years

MADISON, Wis., Sept. 7, 2022 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious respiratory diseases, today announced the completion of enrollment of the first cohort in an age de-escalation clinical trial of M2SR (M2 Deficient Single Replication) live virus vaccine, the company’s investigational supra-seasonal intranasal ...

ByFluGen, Inc.


Meet Obi: The Revolutionary Adaptive Dining Robot

Meet Obi: The Revolutionary Adaptive Dining Robot

Eating should be an independent, relaxing, social, and leisurely time throughout each person’s day, and all of that can be made possible with Obi. Created for individuals with upper extremity strength and mobility challenges, Obi is a simple and easy to use adaptive eating device that provides users with the ability to control what they eat and when. How Obi Works Obi’s ...

ByControl Bionics, Inc.

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