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Platelet Articles & Analysis: This-Year
2 articles found
The CD47 protein on platelets binds with signal regulatory protein alpha (SIRPα) on macrophages which stops macrophages from clearing platelets through phagocytosis and extends the duration platelets circulate in blood. ...
While platelets make up just between 0.5% and 1% of the total blood cells, they're central to body hemostasis. Platelets will kick in the endogenous and exogenous coagulation mechanisms to coagulate blood vessels, convert fibrinogen to fibrin, and create clots with blood cells to close the wounding blood vessels and cause hemostasis. The platelet ...