Preclinical Trial Articles & Analysis: Older
84 articles found
Alfa Cytology has unveiled new services focused on therapeutic antibody development for bladder cancer research.Alfa Cytology, a prominent cancer research services supplier based in New York, proudly announces the launch of its comprehensive services for bladder cancer therapeutic antibody development. This initiative represents a critical advancement in pursuing effective bladder cancer ...
Breast cancer remains one of the most prevalent malignancies affecting women worldwide, necessitating innovative approaches for effective treatment and research. Among the most promising strategies in this endeavor are the use of tumor models for breast cancer and the development of customized antibody-drug conjugates (ADCs). These advancements not only enhance our understanding of the disease ...
Furthermore, it has led to accelerated timelines for preclinical and clinical trials, ultimately benefiting patients awaiting lifesaving therapies. ...
This inclusive service design guarantees the efficacy and safety of drugs for further applications, including preclinical trials and regulatory submission. Complementing their drug development efforts, Alfa Cytology also spearheads vaccine development services for brain tumors, focusing on harnessing the body’s immune response to combat tumors. ...
GMP growth factors and cytokines designed for therapeutic manufacturing are an essential component of defined media. To date, the cell therapy industry has accepted GMP terms for this reagent class, despite the fact that there is no direct oversight by regulators. These proteins are intended for use in further manufacturing processes and do not come into direct contact with patients. In fact, ...
Hence, an extensive lattice of regulations envelops these modalities, mandating rigorous preclinical studies and clinical trials before their eventual public deployment. ...
Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...
CD BioSciences, a biotech company specializing in centrosomal study, has recently launched new services for anti-centrosome antibody development. The services help identify and track centrosomes in experiments, demonstrating the strength of anti-centrosome antibodies as a great tool for centrosome research. The centrosome is a key cellular structure that plays a crucial role in the organization ...
Therefore, the application of computer simulation is expected to reduce reliance on expensive and time-consuming trial-and-error experiments, promoting efficient progress in antibody research and development.Main Challenges in Antibody Discovery1. ...
Alfa Cytology has announced pancreatic cancer vaccine development services to improve the efficacy and safety of related vaccines. Alfa Cytology, a biotech company composed of scientists, bioinformatics, and oncologists, has recently announced its pancreatic cancer vaccine development services to provide further strategies for cancer therapy research. Compared to other solid tumors, ...
Alfa Cytology has announced its small molecule drug development to advance preclinical cancer research. Alfa Cytology, a comprehensive biotech company specializing in cancer research, has recently announced the cancer small molecule drug development services. ...
Alfa Cytology has announced tumor models customization service for pancreatic cancer research. Alfa Cytology, a biotech company specializing in cancer research, has recently unveiled the service on pancreatic cancer tumor model customization to dig into the generation and development of pancreatic cancer and correspondingly provides customized plans for study. Pancreatic cancer is one kind of ...
Host cell proteins (HCPs) are protein impurities produced by genetically engineered strains or cell lines. Some of these proteins are necessary for the survival, reproduction and other normal physiological activities of engineered strains or cell lines. HCPs are purified together with the target product during the production process and cannot be removed. Risks of HCPs In general, HCP ...
At the same time, pre-clinical studies are also significant to assess the efficacy and safety of small molecule drugs in brain cancer before they enter clinical trials in humans. These studies typically involve testing the drug in cell cultures and animal models to assess its ability to target and shrink or destroy cells in the excreta. ...
This process is known as monoclonal antibody products, allowing researchers to induce a renewable source of remedial antibodies for preclinical and clinical disquisition. Before using monoclonal antibodies in clinical trials, they must undergo extensive evaluations to ensure their safety and effectiveness. This includes studies that determine the pharmacokinetics ...
MtoZ Biolabs, leveraging high-precision mass spectrometry technology in conjunction with a chemical proteomics platform, provides you with high quality Collagen Analysis services and other Medical Device services. As a leading biotechnology company, MtoZ Biolabs is committed to providing comprehensive, one-stop CRO testing services to scientific research institutions and pharmaceutical companies ...
What are Adjuvants? Adjuvants, also known as immunomodulators or immune enhancers, are an additive to vaccines. Adjuvants are non-specific immune enhancers that enhance or alter the type of immune response to an antigen. Adjuvants can help antigens induce long-term effective specific immune responses in vivo, leading to higher vaccine efficacy and prolonged protection from immune responses. ...
As more and more ADCs enter clinical trials, the industry is gradually shifting from the use of traditional technologies to the use of newer, more robust methods to connect such complex biomolecules, including strategies using new target antigens, more powerful payloads, new linkers, and advanced coupling technologies.As a combination of macromolecules and small molecules, ADC ...
It is worth noting that the REGN5093-M114 naked antibody itself also has a certain effect in inhibiting tumors and has demonstrated good efficacy in various preclinical models. M1231 The targets of most bispecific ADCs are two different epitopes of the same target, such as the three products above. ...
Hence, an extensive lattice of regulations envelops these modalities, mandating rigorous preclinical studies and clinical trials before their eventual public deployment. ...