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T Cell Articles & Analysis: This-Year
6 articles found
These studies aim to identify whether antibodies or T cells generated against a particular antigen react with similar proteins found in different tissues, which can lead to unintended effects and complications. ...
Examples include CCL2 (MCP-1) and CCL5 (RANTES), both involved in monocyte and T-cell recruitment. l C chemokines (γ-chemokines): These are less common and lack two of the four cysteine residues, such as XCL1 (lymphotactin). ...
Cancer treatment has witnessed transformative advancements over the past few decades, notably with the emergence of CAR-T (Chimeric Antigen Receptor T-cell) therapy. This revolutionary therapy harnesses the body's immune system by genetically engineering T-cells to target and destroy cancer ...
The IP10-loaded platelets targeted and inhibited tumor cells in the B16F10 melanoma model and lessened immunosuppressive regulatory T cell activity through CD40L activation on platelet membranes which led to boosted anti-tumor immunity. ...
These services encompass the design and optimization of molecules, antibody engineering techniques, and a variety of advanced antigen design strategies, all subjected to rigorous quality control to ensure compliance with the highest efficacy and safety standards. Furthermore, CAR T-cell therapy development services opened up new avenues for identifying ...
Among the various forms of immunotherapy, CAR T-cell therapy (Chimeric Antigen Receptor T-cell therapy) has shown promise, particularly in treating acute lymphoblastic leukemia (ALL), especially in children and young adults. This therapy involves genetically modifying a patient’s T-cells to ...