Virus And Vector Articles & Analysis: Older
6 articles found
Currently, the commonly used methods for introducing biological macromolecules into cells include liposome mediated method, virus vector mediated method, electroporation method and microinjection method, etc. ...
The main types of viral vectors used clinically for in vivo gene therapy include adenovirus, adeno-associated virus (AAV), herpes simplex virus (HSV), retroviruses, and lentiviruses. ...
Advances in molecular technology have facilitated the development of other platforms, such as recombinant protein vaccines, nucleic acid vaccines, and viral vector vaccines, which have further diversified global vaccine development. ...
Early in January 2020, sequencing revealed a novel coronavirus (now termed SARS-CoV-2) as the causal factor for the disease designated as COVID-19. The pandemic caused by the virus has unforeseen effects on the global economy and modern society, leading to a global race to find a suitable treatment and a preventive vaccine. ...
ByNuvonis
In addition, viral vectors based on Newcastle disease virus have been previously evaluated as vaccines against e.g. Sars-CoV-2, Ebola, H5N1 influenza, West Nile, and Simian Immunodeficiency virus. Also, oncolytic Newcastle disease viruses and vectors are seen as a promising immunotherapeutic strategy against various cancers. ...
ByNuvonis
Gene therapy vectors are intended to deliver therapeutic genes without making copies of themselves. Whereas other vectors require careful engineering to handicap their ability to replicate in vivo, with AAV we get this property automatically. ...