American Society for Microbiology (ASM)

Pet191 is a cytochrome c oxidase assembly factor in saccharomyces cerevisiae

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Jul. 31, 2008- By: Dennis R. Winge; Oleh Khalimonchuk; Kevin Rigby; Megan Bestwick; Fabien Pierrel; Paul A. Cobine;

The twin-Cx9C motif protein Pet191 is essential for cytochrome c oxidase maturation. The motif Cys residues are functionally important and appear to be present in disulfide linkages within a large oligomeric complex associated with the mitochondrial inner membrane. The import of Pet191 differs from that of other twin-Cx9C motif class of proteins in being independent of the Mia40 pathway.

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