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Reveal the full Complexity of Neutrophils without Activating them with Myelotracker
Neutrophils are the most abundant white blood cells in human blood and central to innate immunity, employing mechanisms such as NET formation to trap and eliminate pathogens.
Labeling neutrophils without altering their function has been challenging; many existing methods activate neutrophils, biasing downstream analyses. Bertin Bioreagent’s Myelotracker uses a peptide-based approach that targets lactoferrin, a neutrophil-associated protein, to achieve precise and selective labeling while preserving the cells’ physiological state.
Evidence from the Application Note demonstrates efficient labeling of human neutrophils under native conditions and in the presence of NETs, enabling analyses that reflect real biological conditions. This supports research in immunology, inflammation, oncology, and broader biomedical fields seeking reliable, non-activating labeling.
Documentation and application notes describe the Myelotracker approach and related bioreagents, providing researchers with detailed guidance on implementation and interpretation.
Original: https://www.bertin-technologies.com/reveal-full-complexity-neutrophils-without-activating-them-with-myelotracker/