Transforming growth factor engages tace and erbb3 to activate pi3k/akt in erbb2-overexpressing breast cancer and desensitizes cells to trastuzumab

Jul. 13, 2008- By: Carlos L. Arteaga; Shizhen Emily Wang; Bin Xiang; Marta Guix; Maria Graciela Olivares; Joel Parker; Christine H. Chung; Atanasio Pandiella

Courtesy ofAmerican Society for Microbiology (ASM)

Departments of Cancer Biology, Medicine, Pathology, Breast Cancer Research Program, Vanderbilt-Ingram Comprehensive Cancer Center, Vanderbilt University School of Medicine, Nashville, TN; Expression Analysis, Durham, NC; Centro de Investigación del Cáncer, CSIC-Universidad de Salamanca, Spain

Transforming growth factor engages tace and erbb3 to activate pi3k/akt in erbb2-overexpressing breast cancer and desensitizes cells to trastuzumab

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