Alfa Cytology products

Cow Breast Cancer Anti-Estrogen Protein 3 (BCAR3) ELISA Kit is designed for the in vitro quantitative analysis of Cow Breast Cancer Anti-Estrogen Protein 3 in tissue homogenates, cell lysates and other biological fluids.

P12FR2 aptamer sodium is a 2'-fluoropyrimidine-modified RNA aptamer targeting human PAUF with an estimated apparent KD of 77 nM. The P12FR2 aptamer sodium inhibits PAUF-induced migration of PANC-1 (human pancreatic cancer cells) in a wound healing assay and suppresses tumor growth in a mouse CFPAC-1 pancreatic cancer model.

KP372-1 is an Akt inhibitor that inhibits proliferation and induces apoptosis and anoikis. KP372-1 is also an NQO1 redox cycling agent that causes DNA damage (including DNA breakage) by generating ROS. KP372-1 can be used in cancer research (such as head and neck squamous cell carcinoma (HNSCC) and pancreatic cancer).

CM03 is a potent ligand for DNA G-quadruplexes (G4s). CM03 stabilizes G4, downregulates more G4-containing genes, and increases the incidence of double-strand break events (DSBs) due to torsional strains on DNA and chromatin structures. CM03 has selective potency against pancreatic cancer cells.

Axl-IN-7 (Chemie 22) is a potent AXL inhibitor. Axl-IN-7 can be used to study Axl-related diseases, such as cancer (such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer and glioma), kidney disease, immune system disease and cardiovascular disease.

KRAS G12C inhibitor 61 inhibits phosphorylated ERK 1/2 in MIA PaCa-2 cells with an IC₅₀ of 9 nM. KRAS G12C inhibitor 61 may be used in studies of pancreatic, colorectal, and lung cancers.

ICy-OH is an iodinated photosensitizer and an effective anticancer agent. ICy-OH can not only be used for deep tissue imaging (λex=640 nm, λem=690-740 nm), but also selectively induce pancreatic cancer cell death through the pyroptosis pathway.

Bis-Pro-5FU is a 5-FU precursor that confers oral bioavailability and improves the safety of 5-fluorouracil (5-FU) chemotherapy regimens. 5-FU is an antitumor antimetabolite that is widely used in colorectal and pancreatic cancer research.