CD Formulation articles

Excipients are the general term for all materials in the prescription except the main active ingredients, such as binders, disintegrants, lubricants, fillers, etc. The choice of excipients for oral solid preparations is affected by factors such as the pharmacological and chemical properties of the raw materials, the preparation process and the price of excipients. There are non-functional excipients and functional excipients. Let’s take a look at the non-functional excipients that are c

Solid preparations for oral administration for children have the advantages of convenient carrying and good stability, but for children, they are prone to dysphagia. The liquid dosage form for oral administration for children not only has benefits like large dispersion and fast absorption, but also can improve the bioavailability of some drugs, which has a greater development prospect and clinical application value.

Disintegration is an early way to evaluate whether a drug is effective. The disintegration time is an important control index for tablets, capsules, and dripping pills. Disintegration means that the solid preparation disintegrates and dissolves or breaks into granules under specified conditions. Except for insoluble coating materials or broken capsule shells, all solid preparations should pass through the screen. Therefore, a d

In industrial production, the surface of the compound may become amorphous due to a small amount of structural damage. It is difficult for conventional instruments to detect this small amount of amorphous substance. Although the content of this amorphous substance is very low, it is very likely to affect the stability of the drug in the production and storage process, resulting in the failure of the entire development. Therefore, even the quantitative analysis of a small amount of amorphous e

Pharmaceutical excipients have important functions such as serving as carriers, improving drug stability, solubilization and slowing down the drug release. They are important ingredients that may affect the quality, safety, and effectiveness of the preparation. Classified by function and purpose, pharmaceutical excipients can be used in different drug forms, including:

Injection, where pharmaceutical excipients are antioxidants, cosolvents, and isotonic regulators, etc.

Oral sol