93 services found
CD Formulation services
CD Formulation - API Physical Modification Services for Drug Development
At present, many drugs are often lower than the concentration required for treatment due to their low solubility, even in saturated solutions. For example, the solubility of chloramphenicol in water is 0.25%, and clinically, more than 12.5% solution is required for intramuscular or intravenous injection. In the pharmaceutical liquid preparation industry, it is necessary to increase the solubility of certain drugs. There are many ways to increase the solubility of drugs, and each has its own advantages. Among them, physical treatment is a very common way. CD Formulation enhances the bioavailability and solubility of drugs through API physical modification services, including nanomilling, micronization, co-crystals, amorphous solutions and dispersions and other technical services. Learn more at https://www.formulationbio.com/api-physical-modification-services.html
CD Formulation - Encapsulation Techniques Services for Drug Development
Solubility and bioavailability issues run through drug metabolism and pharmacokinetic evaluation of candidate compounds, preclinical prescription development, and commercial formulation development. From the toxicological evaluation stage, CD Formulation has a perfect drug metabolism and pharmacokinetic support system, each experiment only consumes milligram-level API, which can help customers select the most suitable solvent for animal experiments in the early stage and shorten the development cycle. In the development of commercial formulations, CD Formulation is familiar with a variety of industrially scalable and enhanced bioavailability drug delivery methods and can use the most scientific and efficient platform technology to rapidly advance the formulation concept from milligram-level high-throughput experiments to production-level. More at https://www.formulationbio.com/encapsulation-techniques-services.html
CD Formulation - Solubility Analysis
CD Formulation can provide you with dissolution profiles of active pharmaceutical ingredients in various solvents (including inorganic solvents with different pH values, organic solvents, simulated intestinal juice or gastric juice, and other solvents) according to your needs. In addition, our scientists specialize in providing solubility enhancement services through a variety of technologies and methods to minimize potential formulation and stability issues. Learn more at https://www.formulationbio.com/solubility-analysis.html
Our Solubility Analysis Services
Building a full range pH solubility profile
Solubility in simulated gastrointestinal media
Solubility improvement
CD Formulation - LogP/LogD/pKa Analysis
CD Formulation can provide you with LogP/LogD/pKa analysis services of APIs and inactive ingredients, and the pKa testing will be performed by our scientists through calculating the LogP or LogD values and measured in various pH values. It will help you to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues. More at https://www.formulationbio.com/logp-logd-pka-analysis.html
CD Formulation - Preformulation
Preformulation is an investigation of physical and chemical properties of a drug substance when used alone or combined with excipients. Early prediction of these properties will generate information useful to the formulator in developing stable and safe dosage forms with good bioavailability.
At CD Formulation , our preformulation services are equipped with advanced instrumentation, and our research team not only have the expertise to handle the most complex formulations, but also have a depth of experience in the pharmaceutical industry and contract service organisations. CD Formulation can offer tailored and rational preformulation development.
https://www.formulationbio.com/preformulation.html
