Creative Biostructure articles

Liposomes have a phospholipid bilayer structure similar to cell membranes. Liposomes are closed ultramicrospheres, similar to an organelle-free artificial cell (only with cell membranes). The artificially manufactured liposome structure is also very similar to the exosomes and vesicles existing in nature. It is precisely due to this property similar to biofilm that it can be used as an efficient, safe, high bioavailabili

Scientists from Rutgers University and Salk Institute have determined the molecular structure of HIV Pol polyprotein, which plays a key role in helping the virus spread itself and systemically. This finding may stimulate new treatments for more than 40 million AIDS patients worldwide.

 Their findings, published in Science Advances, could guide the development of drugs that bind to the protein and block its function.

 "Drug molecules require a specific structure to sp

Gene editing is one of the latest breakthroughs in biology. The well-known CRISPR-Cas gene editing system confers immunity against foreign DNA to prokaryotes (organisms lacking a cell nucleus). Since the discovery of CRISPR gene editing technology, scientists have revealed how CRISPR-cas proteins evolved from their precursors. This knowledge will help them develop other small new genome editing tools for gene therapy.

At the University of Tokyo, Professor Osamu Nureki's t

A team of scientists from around the world, including from Trinity College Dublin, has obtained high-resolution structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it, thereby inhibiting disease-causing bacteria. Their work is important amid growing concerns about rising antibiotic resistance.

The scientists, led by Martin Caffrey, Emeritus Fellow of Trinity's Faculty of Medicine and School of Biochemistry and Immunology, u

Introduction

Within the intricate world of cellular biology, membrane scaffold proteins play a crucial role in maintaining the structural integrity and functionality of cell membranes. These proteins act as building blocks, providing support and stability to the delicate lipid bilayer that surrounds and protects the cell. In this blog post, we will explore the fascinating world of membrane scaffold proteins, their functions, and their significance in cellular architecture