mimiX Biotherapeutics products

Create biological architectures with sound. Sound Induced Morphogenesis (SIM) is a gentle, fast, and easy method to generate multi-cellular, spatially orchestrated tissue constructs using sound waves. This versatile method addresses necessities in the broad field of life sciences, finding application in tissue engineering, regenerative medicine, or pharmaceutical research for drug discovery.

KYTO is a chemically defined, synthetic hydrogel that bears biologically active sites. An MMP-cleavable crosslinker allows for potential cell spreading and migration. The hydrogel can be customised to bear a cell adhesive peptide, RGD, to further fine-tune the properties for specific applications. KYTO increases in viscosity after 8 to 10 minutes, enabling a dense and well-defined cell pattern to be formed followed by enhanced stability of the pattern when the dish is moved from cymatiX to the incubator for complete gelation.

ZAVA is a chemically defined, synthetic hydrogel that allows you to exploit the full potential of SIM – long term patterning, gelation upon demand, and biologically active sites. The hydrogel is photosensitive and crosslinks upon irradiation at 405 nm. MMP-cleavable sites and RGD peptides allow for potential cell spreading and migration and promote cell adhesion.

LUMPO is a chemically defined, synthetic hydrogel that crosslinks upon irradiation at 405 nm. This hydrogel does not bear any biologically active sites. The viscosity has been optimised to allow for prolonged patterning of single cells or particles. Gelation on demand is ideal to exploit the method of sound induced morphogenesis.

BAKU is a chemically defined, synthetic hydrogel based on Dextran and PEG. This hydrogel does not bear any biologically active sites. Viscosity and gelation kinetics were adapted to allow for patterning of individual cells or particles.