Protheragen articles

The Hargreaves test is one of the classic experiments used to detect thermal pain responses in rodents. The test is commonly used to quantify the thermal threshold to radiation or infrared thermal stimulation in the hind paw of mice and rats.

In the Hargreaves test, a radiant or infrared heat source is usually placed underneath the rodent and aimed at the plantar surface of the rodent's hind paw

In many cases, gene therapy requires a vector to deliver the gene therapy drug to the target cell. Viral vectors have been one of the most widely studied vectors due to their outstanding transduction efficiency and other significant advantages. Viral vector-based gene therapy has now achieved good clinical results. More than a dozen viral gene therapy products have been approved for the treatment of cancer, infectious diseases, and rare single-gene disorders. The main types of viral vectors u

Stroke, also known as transient ischemic attack or cerebrovascular accident, is an acute brain disease. Usually, a sudden rupture of a blood vessel in the brain or a blockage of a blood vessel that prevents blood from flowing to the brain can cause damage to brain tissue, resulting in a stroke.

Long-term strokes can lead to brain damage, disability and even death. The brain serves as a high-level nerve center that controls many aspects of the body, including sensation, co

The diagnosis and treatment of rare diseases have long been a daunting challenge due to their complex and often undefined nature. However, with recent advancements in technology, specifically in the realm of genomics, whole genome sequencing (WGS) has emerged as a powerful tool that has revolutionized the diagnosis and management of rare diseases. This groundbreaking technique offers hope to countless individuals and their families who have suffered from the uncertainties and lack of answers

Rare diseases, also known as orphan diseases, affect a small percentage of the population, making them particularly challenging to diagnose and treat. However, thanks to advancements in medical research and technology, significant progress has been made in the field of rare disease research, from developing accurate diagnostic tools to making effective small-molecule drugs.

One of the biggest hurdles in treating rare diseases is accurately diagnosing them. Many of these c