AROTEC - Model ATL04 - Liver Cytosol Antigen 1 (LC-1) - Datasheet

LC-1 is a marker for autoimmune hepatitis (AIH) type II and antibodies against LC-1 are found to be detected in up to 50% of cases. Immunofluorescence of LC-1 is often not identified due to the brightness of LKM-1 obscuring accurate visualisation. Some occurrences of anti-LC-1 in conjunction with antinuclear antibodies (ANA) and smooth muscle antibodies (SMA) in patients with chronic hepatitis C and autoimmune hepatitis, is known. Some case studies have shown that anti-LC-1 is found as the only serological marker in patients with AIH type II.