B??HLMANN - Model anti-MAG - Autoantibodies ELISA - Brochure

The anti-MAG Autoantibodies ELISA has outstanding sensitivity and specificity. In a study with 68 involved patients, the anti-MAG Autoantibodies ELISA was considerably more sensitive compared to Western Blot (Kuijf M. et al., 2009). High titers of IgM anti-MAG antibodies are associated with sensory motor demyelinating peripheral neuropathy. The possibility of MAG antibody involvement in a suspected neuropathy may essentially be ruled out if a MAG IgM negative result is obtained. Detection of MAG IgM antibodies by ELISA based on human MAG antigen is significantly more sensitive and specific than Western Blot or IFA assays using primate antigen (Jaskowsky T. et al., 2008; Kuijf M. et al., 2009).