https://www.kouraglobal.com/products/medical/zephex134a/index.html - Brochure

Relied upon by leading Metered Dose Inhaler (MDI) manufacturers for over twenty years, Zephex® 134a is by far the most widely used medical propellant in the world. Present in over 70% of MDIs it is used in nearly all the major high-volume formulations including salbutamol sulphate, beclomethasone diproprionate, ipratropium bromide, fluticasone and their numerous combinations. Koura manufactures Zephex® 134a at dedicated facilities in the UK which are operated to cGMP standards. From the UK Zephex® 134a is then shipped globally to pharmaceutical customers in a fleet of dedicated isotanks and packages.