inflammatory-disease Downloads
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Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from ...
Changes in Albumin measurements are used in the diagnosis and treatment of inflammatory processes or disease of the liver or kidney. Bromocresol green (BCG) binds, quantitatively and specifically, with the albumin, giving a green/blue compound whose colour intensity is proportional to the albumin concentration in the tested ...
Over the past two decades great improvements in therapy of chronic inflammatory diseases have been made. The rise of TNFα biologics like infliximab has been a significant step forward to ameliorating disease course and keeping inflammations at remission levels for prolonged periods of time. Patients with too low drug concentrations have worse outcomes than those with adequate drug levels. ...
Over the past two decades great improvements in therapy of chronic inflammatory diseases have been made. The rise of anti TNFα biologics has been a significant step forward to ameliorating disease course and keep inflammations at remission levels for prolonged periods of time. Adalimumab is the first anti TNFα biologic on the market approved for patient self-administration by ...