Lumigen - Model AGP-SP-2 - Heavily Glycosylated Protein - Brochure

Alpha-1-acid glycoprotein (AGP) is a heavily glycosylated protein that is expressed in the liver and secreted into blood. It is a positive acute phase reactant; liver expression and serum concentrations increase as a result of injury, infection or disease. In studies at Life Diagnostics, Inc. we found that serum AGP levels increased approximately 25-fold twenty-four hours after rats were challenged with lipopolysaccharide. AGP is an excellent acute phase biomarker in rats.