Mentanine Pre-Clinical Trial Results - Brochure

One of The Characteristics of dopamine cells is that they have a tonic mode of firing and burst mode of firing. Therefore, we analyze both the frequency and burst changes following infusions. The left graph is looking at the frequency of VTA dopamine cells. The Y-axis is frequency %baseline). Just to clarify what this means: if we look at the 100ng CBD group, it shows about 85%. This means that with an intra-NAc infusion of 100ng CBD, the dopamine cell would decrease in frequency by about 15%.