C2i Genomics Partners with OncoDNA to Bring AI-Powered Liquid Biopsy for Cancer Diagnostics Across Europe

C2i Genomics, a cancer intelligence company, today announced expansion into Europe through a strategic partnership with OncoDNA, a genomic and theranostic company specializing in precision medicine for the treatment of patients with cancer and genetic diseases. With entities based in Belgium, France, Spain and the UK, OncoDNA has built an outstanding network of cancer clinicians-researchers across Europe. The company will act as a primary lab partner, operating C2i’s whole-genome sequencing (WGS) and minimal-residual disease (MRD) cancer monitoring platform for European clinical research projects. This partnership will also support a first-of-its-kind interventional clinical trial in France led by Gustave Roussy.

As of 2021, the American Cancer Society reports that Europe accounts for 22.8% of the world’s total cancer cases and 19.6% of cancer deaths, but currently, there are few local genomic providers of cancer detection and treatment monitoring that operate in the EU market. OncoDNA, amongst others, has been providing tissue-based biomarker testing and personalized liquid biopsy to support oncologists in their clinical recommendations. The C2-intelligence platform, which uses AI-pattern recognition and whole-genome analysis, will use advanced cancer genomics and liquid biopsy products to support rapid and accurate detection of cancer, monitor disease progression and evaluate therapeutic efficacy in clinical research settings. This is all done to enable informed and timely personalized treatment decisions and support the development of more effective cancer treatments through pharma drug development partnerships. 

“OncoDNA’s extensive lab operation, data interpretation infrastructure alongside its commercial expertise in bringing advanced cancer genomics and liquid biopsy products to market will help accelerate C2i’s expansion and commercialization in Europe,” said Asaf Zviran, CEO and Co-Founder of C2i Genomics. “This partnership will support clinical and pharma research services, and will ultimately provide the C2-intelligence platform for clinical research use.”

As part of the partnership, C2i and OncoDNA will collaborate on a 750+ patient interventional clinical trial led by Gustave Roussy leading comprehensive cancer center in Europe. C2i, with the help of OncoDNA, will provide cancer monitoring and analytic services to test the clinical utility of escalating metastatic treatment to patients with a high risk of cancer recurrence after standard of care. This basket trial will include detection of circulating tumor DNA (ctDNA) across various solid tumors, including lung cancer, breast cancer, sarcoma and gastrointestinal (GI) cancers. The study aims to provide conclusive evidence of the clinical and economic benefits of C2i’s cancer detection technology across various solid cancers. 

“OncoDNA shares with C2i the vision of making precision medicine in oncology a reality for patients, allowing for more effective and individualized therapy decisions,” said Jean-Pol Detiffe, Chief Strategy & Innovation Officer, and Founder of OncoDNA. “C2i’s whole-genome technology provides ultra-high sensitivity with significantly reduced lab operation complexity, eliminating the need to develop a patient-specific assay, and allowing rapid and high throughput solution for cancer patients across the EU. This partnership completes our offering of genomic services, NGS tests and data interpretation software suite.” 

This partnership is C2i’s first commercial entry into the European market. It comes after a year of tremendous global growth and expansion, namely into South East Asia through a partnership with NovogeneAIT, into the U.S. with Premier Inc. and the Chinese market with NuProbe Global.