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Ionicon PTR-TOF instruments deployed for COVID-19 detection in breath

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May. 14, 2020

SARS-CoV-2 currently has the world in its grasp. A quick, non-invasive test to identify an infection would be a tremendous step forward. There is a high probability that this disease can be detected in the exhaled breath but also monitoring the impact of treatment or medication in exhaled breath is highly relevant. IONICON PTR-TOF systems have become the de-facto standard for real-time breath analysis. Learn what they offer for COVID-19 detection in breath.

Advantages of breath gas analysis with IONICON PTR-TOFMS and dedicated BET inlet system


Breath gas analysis of volatile organic compounds (VOCs) has become a growing field of research in recent years. In the blood gas exchange in the lungs alveoli Carbon dioxide is released into and Oxygen is taken up from the inhaled air. This exchange also applies to volatile metabolites that are produced in the body or in the lungs directly. By this mechanism researchers are trying to detect volatile biomarkers in exhaled breath that are indicative for a disease or for the response to pharmacological treatments. Sampling exhaled breath is non-invasive and simple. But the analysis is the challenge: Several hundred volatile compounds have so far been identified in exhaled breath and their range of concentrations, typically in the parts-per-billion range, are a challenge to most modern analyzers.

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