Antigen Interaction Articles & Analysis: Older
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For NALFIA, both forward and reverse primers are typically labeled with biotin and another antigen with high antibody affinity (e.g., digoxin (DIG), carboxyfluorescein (FAM), and/or FITC). ...
Each of these use cases requires identification of the antibody component that directs that particular action. In the case of improving antigen affinity, it is necessary to know and understand the residues present on the variable light and heavy chains and the interactions made between the antibody and the antigen. ...
The platform also supports the ability to study antibody-antigen interactions that can inform bio-preparedness and threat response, such as rapid test deployment and vaccine development. ...