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Gentronix - 24-well Mini Ames Agar Based Screen
FromGentronix Ltd
Using a microwell format, the Ames 24-well study provides predictivity of the OECD 471 Ames study in comparable conditions but using just 5% of the test item and is also conducted in solid agar. This makes the 24-well version of the Ames test highly amenable to screening, with TA98 & TA100 providing coverage for the vast majority of all know mutagenic substances.
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Advantages for Screening
- Agar based, TA98 & TA100 ± S9
- Results comparable to full plate format
- Requires 20 mg compound
- Quick, cost effective, high quality results
- 24-well Test strains TA98, TA100
- Metabolic activation Typically, induced rat liver S9, other sources
- available
- Replicates 3 Wells per test concentration
- Typical test item requirements 20mg
- Study Duration < 3 Weeks
- Endpoint Mutagenicity