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MedChemExpressModel Kyotorphin - 70904-56-2

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Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients[1].
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Kyotorphin

MCE China:Kyotorphin

Brand:MedChemExpress (MCE)

Cat. No.HY-122381

CAS:70904-56-2

Purity:99.79%

Storage:Sealed storage, away from moisture Powder -80°C 2 years -20°C 1 year *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Shipping:Room temperature in continental US; may vary elsewhere.

Description:Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients.

In Vitro:The analgesic effect of kyotorphin is determined by means of the hot-plate test, with an ED50 value of 5.3 μg/animal (15.7 nmole/animal)[1].

IC50 & Target:Human Endogenous Metabolite

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References:

[1]. Takagi H, et al. Morphine-like analgesia by a new dipeptide, L-tyrosyl-L-arginine (Kyotorphin) and its analogue. Eur J Pharmacol. 1979;55(1):109-111.  [Content Brief]

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