
MedChemExpress - Model Eldelumab - 946414-98-8
Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease[1][2].MCE products for research use only. We do not sell to patients.
Eldelumab
MCE China:Eldelumab
Brand:MedChemExpress (MCE)
Cat. No.HY-P99190
CAS:946414-98-8
Synonyms:BMS-936557; MDX-1100
Purity:96.76%
Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping:Shipping with dry ice.
Description:Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease.
IC50 & Target:CXCL10 (IP-10)[1][2]. Clinical Trial
Species:Human
Isotype:Human IgG1(K214R) kappa
Recommend Isotype Controls:Human IgG1 (K214R) kappa, Isotype Control
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References:
[1]. Gupta RK, et al. Drug repurposing for COVID-19 based on an integrative meta-analysis of SARS-CoV-2 induced gene signature in human airway epithelium. PLoS One. 2021 Sep 28;16(9):e0257784. [Content Brief]
[2]. Asquith DL, et al. Targeting cell migration in rheumatoid arthritis. Curr Opin Rheumatol. 2015 Mar;27(2):204-11. [Content Brief]
Brand introduction:
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