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MedChemExpressModel Eldelumab - 946414-98-8

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Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease[1][2].
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Eldelumab

MCE China:Eldelumab

Brand:MedChemExpress (MCE)

Cat. No.HY-P99190

CAS:946414-98-8

Synonyms:BMS-936557; MDX-1100

Purity:96.76%

Storage:Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping:Shipping with dry ice.

Description:Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease.

IC50 & Target:CXCL10 (IP-10)[1][2]. Clinical Trial

Species:Human

Isotype:Human IgG1(K214R) kappa

Recommend Isotype Controls:Human IgG1 (K214R) kappa, Isotype Control

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References:

[1]. Gupta RK, et al. Drug repurposing for COVID-19 based on an integrative meta-analysis of SARS-CoV-2 induced gene signature in human airway epithelium. PLoS One. 2021 Sep 28;16(9):e0257784.  [Content Brief]

[2]. Asquith DL, et al. Targeting cell migration in rheumatoid arthritis. Curr Opin Rheumatol. 2015 Mar;27(2):204-11.  [Content Brief]

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