Lipotek

LipovaxModel Fg115 - Adjuvanted Delivery Vehicle for Recombinant Antigens

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Lipovax-Fg115 is an adjuvanted delivery vehicle for recombinant antigens. The platform exploits the commonly used his-tag to attach multiple copies of one or more type of antigens to the surface Lipovax-Fg115 particles. Our proprietary Fg115 molecules are also attached to the liposomes to stimulate the TLR5 receptor. The platform improves vaccine internalisation by dendritic cells and results in increased cross presentation. In vivo this translates in increased T cell and antibody and responses.

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  • Optimal size for dendritic cell uptake and processing
  • Improved internalisation and cross presentation
  • Synthetic and well defined components
  • Not based on cationic liposomes
  • Good safety profile
  • Simple formulation
  • High homogeneity and reproducibility
  • Antigen stabilisation and half life improvement
  • Applicable to antigens of varying size (from peptides to large proteins)