Veravas, Inc.

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Veravas, Inc.
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Veravas - Model VeraPrep - Antibody ...

Veravas - Model VeraPrep - Antibody Detection Kit

FromVeravas, Inc.

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Multiplex detect antibodies in serum, plasma or saliva. The VeraPrep Antibody Detection Kit provides scientists with a state-of-the-art research tool to easily and quickly develop new tests to multiplex detect and measure immunoglobulins against new and emerging pathogens as well as autoantibodies against cardiac, neurologic, and cancer biomarkers. The ability to preanalytically remove sample interferences from a larger sample and subsequently concentrate makes it possible to detect antibodies in low abundance. The Kit includes all reagents required to support researchers’ test developments for up to 50 samples. All that’s needed for a new test is for you to switch the biotin labeled antigen used on the proprietary streptavidin capture beads and the kit will multiplex detect IgA, IgG and IgM antibodies against the new antigen.

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CONDITION – condition beads capture and remove sample interference
CAPTURE – capture beads selectively capture antibodies from the cleaned sample
CLEAN – remaining sample matrix is washed away leaving only the antibodies of interest
CONCENTRATE – antibodies of interest are resuspended in a smaller volume of “crystal” clear liquid
CONJUGATE – conjugate specific for IgA, IgG and IgM attaches to the antibodies of interest
CLEAVE – conjugate is released from the antibodies and the capture beads are left behind
CHARACTERIZE – IgA, IgG and IgM are easily detected and simultaneously analyzed in a single test

Serology
Autoantibodies against cardiac biomarkers, neuromarkers, and cancer antigens
Autoimmune disease
Vaccine efficacy
Therapeutic immune response

For Research Use Only (RUO)
Includes all reagents required to test 50 samples
Easily automated using a liquid handler
Removes sample interference prior to the test
Utilizes a proprietary magnetic streptavidin bead for use with biotinylated antigens
Captures and multiplex measures IgA, IgG and IgM immunoglobulins against any antigen of interest
Concentrates low abundance antibodies to improve likelihood of detection
Supports development of quantitative, semi-quantitative or qualitative assays
Facilitates faster test development
Can use serum, plasma, saliva, and saline oral rinse sample types

CONDITION BEADS – targets and removes heterophilic and autoantibody interference
CAPTURE BEADS – streptavidin coated to bind biotinylated antigens
CAPTURE BEAD STORAGE BUFFER – wash and store antigen coated capture beads
CLEAN BUFFER – wash the sample matrix and excess conjugate from the capture beads
CONJUGATE – anti-IgG (AlexaFluor488), anti-IgM (AlexaFluor555) and anti-IgA (AlexaFluor647) detection antibodies
CALIBRATORS – beads coated with purified human IgA, IgG and IgM to generate antibody-specific calibration curves (RFU vs. Concentration)
CLEAVE BUFFER – elute conjugate from the capture beads
CHARACTERIZATION BUFFER – read the conjugate
CONTROLS – low and high for quality control