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LOGAN - Model DISSO 3 - Automated Drug Dissolution Tester with USP Apparatus 3 or 7
The DISSO-3 reciprocating cylinder apparatus is designed for assessing active pharmaceutical ingredient (API) release characteristics across various solid dosage forms such as sustained-release, enteric-coated, soft capsules, and chewable tablets. This system is vital for evaluating dissolution profiles under different pH conditions, which are critical for formulating effective drug dosage forms. Understanding how APIs release in gastrointestinal conditions can significantly impact the drug`s efficacy and patient outcomes. Logan provides not only standard dissolution testers but also offers custom solutions to cater to specific analytical needs, ensuring comprehensive drug testing capabilities. By enabling precise control and replication of different physiological conditions, the DISSO-3 aids in compliance with USP testing standards, providing drug developers valuable insights into their products` performance.
The DISSO-3 reciprocating cylinder apparatus is a valuable tool for evaluating API release characteristics for sustained-release, enteric, soft capsules, chewable tablets, or any solid dosage form where evaluation of different pH conditions is important.
- Available in 6-row or 12-row configurations
- 300 mL or 1 L vessel options
- 300 mL: eight sample holders x six rows
- 1 L: eight sample holders with eight 1 L positions
- Unique anti-evaporation vessel cover significantly reduces solvent evaporation and prevents cross contamination
- Ability to configure multi-point sampling per row for dissolution method screening
- Programmable stroke distance to ensure USP compliance with different dosage types
- Multiple mesh screen sizes and materials to choose from
- Automated media replacement to ensure sink conditions
- Post-test wash routines
- Storage up to 20 methods
- Administrator, manager, operator security levels
- 21 CFR Part 11, USP, EP, JP, CP compliant
USP Apparatus 3 is commonly used for testing of drugs such as sustained-release, enteric-coated, soft capsules, and chewable tablets.
- Available camera monitoring system can record the entire process of drug release
- Compatible with the Logan Permetro bioequivalence (BE) tester
- Ability to run with on-line UV