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GS-InternationalModel CAS -94-09-7 - Benzocaine

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Benzocaine is a non-water-soluble local anesthetic, used externally as a spray, used for postoperative trauma pain relief, ulcer pain, and has analgesic and antipruritic effects. Benzocaine products are used as local anesthetics for skin and mucous membranes. The characteristics of the action are rapid onset, analgesic effect in about 30 seconds, and no permeability to mucous membranes, low toxicity, and no effect on the cardiovascular system and nervous system. Protective agent used to block sunlight, Used in cosmetics to absorb ultraviolet rays, local anesthetics, and used for pain relief of wounds, ulcers and hemorrhoids.

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  • CAS No.: 94-09-7
  • Molecular Formula: C9H11NO2
  • Molecular Weight: 165.19 g/mol
  • Appearance: White crystalline powder or shiny crystals; odorless with a slightly bitter taste
  • Melting Point: 88–92°C (USP specification: range ≤2°C)
  • Boiling Point: 183–184°C (at 14 mmHg)
  • Density: 1.17 g/cm³

Safety and Handling

  • PPE: Gloves, goggles, and lab coat required; avoid inhalation .
  • First Aid: Rinse skin/eyes with water; seek medical attention for ingestion .
  • Environmental: Prevent release into waterways due to aquatic toxicity

Medical Uses    

  • Topical Anesthetic: Used for mucosal surfaces (oral, rectal, skin) to relieve pain from ulcers, burns, or minor surgeries
  • Dental Procedures: Pre-treatment for tooth extraction or cavity filling
  • Otic Preparations: Relief of ear pain

Industrial Applications   

  • Cosmetics: Added to creams, gels, and sprays for localized pain relief (e.g., sunburn, insect bites)
  • Food Industry: Flavoring agent (bitter-masking properties)
  • Chemical Intermediate: Synthesis of procaine, oxethazaine, and other derivatives