Synergy Biomedical, LLC

BioSphereModel Putty - Bioactive Bone Graft

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BioSphere Putty is based on an innovative form of 45S5 bioactive glass.  The Putty utilizes Synergy`s unique spherical bioactive glass particles with a optimized, bimodal size range. The combination of the BioSphere particles and a resorbable, phospholipid carrier results in a bioactive Putty with the highest bioactive glass content on the market, excellent handling, and improved bone healing..

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Bone graft composed of bioactive glass

  • Bioactive glass forms a bone-like mineral layer on its surface that promotes bone formation and attachment [1]
  • Bioactive glass dissolution ions stimulate cells involved in bone healing [2]

Unique spherical particle shape

  • Spherical particles provide uniform resorption and ion release
  • 3-D sphere packing provides an optimal porosity for bone formation throughout implant site

Bimodal size particle range

  • Small spheres (10%) provide fast resorbing particles that starts the bone healing process with a quick release of dissolution ions
  • Large spheres (90%) provide slower resorbing particles that provides a scaffold for bone formation and longer term ion release

Resorbable phospholipid carrier

  • Allows BioSphere Putty to have a high bioactive glass particle content
  • Creates a moldable putty with excellent handling and cohesiveness
  • Naturally occurring phospholipids are absorbed by the body and used by local cells

Highest bioactive glass content on the market (80% w/w)

  • Provides complete filling of a bone defect with bioactive glass particles
  • Results in better particle contact with the edges of the bone defect which promotes faster healing
  • Minimizes particle settling after carrier resorption

Excellent handling, resistance to irrigation, and graft placement

  • Putty can be easily customized to fit the surgical site
  • Does not wash away with exposure to blood or irrigation fluid
  • Designed to be mixed with particulate autograft

Glass Content
BioSphere® Putty has the highest bioactive glass content of any bone graft putty or sheet on the market.
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Superior Handling

The use of a highly moldable  phospholipid carrier results in a cohesive putty with superior handling that does not fall apart.
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Bone Healing 
The spherical particles in BioSphere® Putty have improved the bone healing properties of bioactive glass.

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