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GeneVax - Model prime/VesiculoVax - Boost Therapeutic Vaccine for HSV-2
Auro Vaccines is developing a GeneVax prime/VesiculoVax boost therapeutic vaccine for herpes simplex virus type-2. This vaccine is designed to ameliorate disease and transmission by preventing HSV-2 reactivation and shedding.
Program Status:
Antigen discovery stage. Further development of this candidate is currently on hold and is available for out-licensing or co-development.
Unmet Medical Need:
Herpes simplex virus type 2 is a sexually transmitted virus that causes watery lesions in the skin and mucus membranes of the genitals. It establishes latency in neurons, from where it can sporadically reactivate to cause shedding/transmission with or without new sores. The CDC estimates that 776,000 people in the United States are newly infected each year. Currently, control is only possible with life-long drug treatment.